Translational Research Without Silos

Sigma Biotech integrates research, regulatory, quality, and clinical strategy to accelerate biomedical innovation from concept to patient impact.

Mission: Technology development and translational research.

Note: All content and engagements are subject to Sigma’s internal quality and regulatory review.

Integrated Expertise

  • • Translational Strategy
  • • Regulatory & Quality
  • • Clinical Research
  • • Post-Market Evidence

20+

Years Experience

Global

Regulatory Reach

End-to-End

Lifecycle Support

Integrated

One-Firm Model

What is Translational Research?

Translational research bridges the gap between discovery and real patient impact. It takes promising science and shapes it into something that can be safely tested, validated, approved, and used in clinical practice.

Sigma simplifies complex decisions by aligning evidence needs, regulatory expectations, clinical feasibility, and operational efficiency — early, not late.

What we simplify

  • • Burden of proof & evidence planning
  • • Regulatory pathways & submission expectations
  • • Clinical endpoints & feasibility tradeoffs
  • • Quality systems & design controls

Proven Outcomes

Record-Setting Clinical Execution

Leadership experience includes supporting a fastest-enrolling clinical study leading to subsequent PMA approval — demonstrating rigorous strategy aligned with execution.

Clinically Validated Tools

Co-development of the clinically validated SPOT GRADE bleeding severity scale — supporting consistent clinical assessment and evidence quality.

Why Sigma Biotech

Sigma (∑) represents the summation of all moving parts in biotechnology development.

We reduce redundancy, mitigate downstream risk, and align science with regulatory and commercial reality.

Design With the End in Mind

Regulatory, clinical, quality, and end-user needs considered from day one.

One Integrated Team

An extension of your internal team — not a vendor.

Services

Integrated capabilities designed to support innovation across the full development lifecycle.

Translational Strategy

Align science, regulation, and clinical execution.

Regulatory & Quality

Strategic submissions and quality systems.

Clinical Research

Protocol design, operations, and evidence generation.

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Areas of Expertise

Medical Devices Diagnostics AI / ML Combination Products CRO Strategy Longevity Research

Cross-Disciplinary Focus

  • • Pre-clinical to post-market
  • • Regulatory-aware design
  • • Real-world evidence

Ready to Build Smarter?

Bring clarity, structure, and translational rigor to your development program.